| C | Programmiersprache C |
| CAAD | Computer Aided Architectural Design (Computergestütztes architektonisches Planen und Entwerfen) |
| CA | Certificate Authority |
| CAD | Computer-Aided Design (Computerunterstütztes Design) |
| CAE | Computer-aided engineering |
| CAF | Composite Application Framework |
| CAM | Computer-aided manufacturing |
| CAN | Controller Area Network oder |
| Content Addressable Network |
| CAPI | Common ISDN Application Programming Interface |
| CAPWAP | Control And Provisioning of Wireless Access Points |
| CARP | Common Address Redundancy Protocol |
| CAS | Column Address Strobe: Dynamic Random Access Memory#CAS |
| CAS | Computeralgebrasystem |
| CAT | Catalog Service |
| CAV | Constant Angular Velocity |
| CAVE | Cave Automatic Virtual Environment |
| CAW | Computer-Aided Woodcut (zu Deutsch rechnerunterstützter Holzschnitt) |
| CBO | Cost Based Optimizer, kostenbasierten Optimizer für Zugriffe auf Datenbanksätze |
| CC | Carbon Copy oder |
| Creative Commons |
| C Compiler |
| CCD | Charge-coupled Device |
| CC/PP | Composite Capability/Preference Profiles |
| CCU | Camera Control Unit |
| CD | Compact Disc |
| CDATA | Character Data |
| CDC | Connected Device Configuration |
| CDE | Common Desktop Environment |
| CDMA | Code Division Multiple Access |
| CDN | Content Delivery Network |
| CD-R | Compact Disc Recordable |
| CD-ROM | Compact Disc Read-Only Memory |
| CD-RW | Compact Disc ReWriteable |
| CEPT | Conférence Européenne des Administrations des Postes et des Télécommunications |
| CET | Control-flow Enforcement Technology |
| CFML | ColdFusion Markup Language |
| CFSM | Communicating Finite State Machines |
| CGA | Color Graphics Adapter |
| CGI | Common Gateway Interface |
| CHAP | Challenge Handshake Authentication Protocol |
| CHS | Cylinder Head Sector |
| CICS | Customer Information Control System |
| CIDR | Classless Inter-Domain Routing |
| CIF | Common Intermediate Format |
| CIFS | Common Internet File System |
| CIM | Computer-integrated manufacturing oder |
| Common Information Model |
| CISC | Complex Instruction Set Computer |
| CLDC | Connected Limited Device Configuration |
| CLI | Call Level Interface oder |
| Command Line Interpreter oder |
| Common Language Infrastructure |
| CLOB | Character Large Object |
| CLM | Certificate Lifecycle Manager |
| CLR | Common Language Runtime |
| CLTS | Connectionless Transport Service, ein verbindungsloser Service, beispielsweise UDP |
| CLV | Constant Linear Velocity |
| CM | Content-Management |
| CMM | Capability Maturity Model oder |
| Color Management Module |
| CMOS | Complementary Metal Oxide Semiconductor (dt. Komplementärer Metall-Oxid-Halbleiter) |
| CMS | Content-Management-System |
| CMYK | Cyan Magenta Yellow Key, siehe CMYK-Farbmodell |
| CO | Callable Object |
| COBOL | Common Business Oriented Language |
| CODASYL | Conference on Data Systems Languages |
| COM | Component Object Model oder |
| Computer on Module (Kernhardware eines Computers implementiert auf einem steckbaren Modul) |
| COMA | Cache-only-Memory-Access |
| CORBA | Common Object Request Broker Architecture |
| COTS | Connection Oriented Transport Service, ein verbindungsorientierter Service, wie beispielsweise TCP |
| COW | Copy-On-Write, Verfahren zur Vermeidung von überflüssigen Kopien von Daten |
| CPL | Call Processing Language oder |
| Combined Programming Language oder |
| Common Public License |
| CP/M | Control Program/Monitor, später: Control Program for Microcomputers |
| CPPM | Content Protection for Pre-Recorded Media, Kopierschutzverfahren der DVD-Audio |
| CPRI | Common Public Radio Interface |
| CPRM | Content Protection for Recordable Media |
| CPSL | Common Pattern Specification Language |
| CPU | Central Processing Unit |
| CPUID | Central Processing Unit Identification |
| CRC | Cyclic Redundancy Check, Verfahren zur Ermittlung von Übertragungsfehlern |
| CRE | Content Relationship Engine |
| CRL | Certificate Revocation List |
| CRM | Customer-Relationship-Management |
| CRT | Cathode Ray Tube |
| CRUD | Create, Read, Update, Delete (Datenbankoperationen) |
| CSA | Common-Scrambling-Algorithmus oder |
| Connector, Switch, Attenuator theory |
| CSI | Common System Interface |
| CSM | Compatibility Support Module |
| CSMA/CA | Carrier Sense Multiple Access/Collision Avoidance |
| CSMA/CD | Carrier Sense Multiple Access/Collision Detection |
| CSP | Communicating Sequential Processes |
| CSS | Cascading Style Sheets oder |
| Content Scramble System |
| CSV | Character Separated Values, Comma Separated Values |
| CTF | Capture the Flag |
| CTL | Complex Text Layout |
| CTS | Clear To Send |
| CUDA | Compute Unified Device Architecture |
| CUI | Character User Interface, d. i. Zeichenorientierte Benutzerschnittstelle |
| CUoD | Capacity Upgrade on Demand |
| CUPS | Common Unix Printing System |
| CVS | Concurrent Versions System |
| CWM | Common Warehouse Metamodel |